Interstate 22 (Mississippi)

Interstate 22
Interstate 22 highlighted in red.
Route information
Length:	213.0 mi (342.8 km)
Existed:	2012 (2012) – present
Major junctions
West end:	US 78 near Byhalia, MS
	US 45 in Tupelo, MS US 43 / US 278 / SR 171 in Hamilton, AL US 78 / SR 5 in Graysville, AL
East end:	I‑65 near Birmingham, AL
Location
States:	Mississippi, Alabama
Highway system
Interstate Highway System Main Auxiliary Suffixed Business Future Mississippi State Highway System Interstate US State Alabama Highways Interstate US State ← MS 21 MS MS 22 → ← SR 21 AL SR 22 →

Interstate 22 (I-22) is an Interstate Highway that follows the U.S. Route 78 (US 78) corridor on a 213-mile-long (343 km) route from Byhalia, Mississippi south of Memphis, Tennessee, to Birmingham, Alabama. I-22 indirectly connects I-240, I-40, I-55, and I-69 in the northwest with I-65 and I-20/I-59 in the southeast. When designated in 2012, it was designed to close a gap in the Interstate network allowing more direct connections between cities in the southeast (such as Atlanta and Birmingham) with those of the Great Plains (such as Oklahoma City and St. Louis).

Along its way through the two states, I-22 serves the towns of Jasper, Winfield, and Hamilton, Alabama and Fulton, Tupelo, New Albany, and Holly Springs, Mississippi. All portions of this highway were either built new or converted to Interstate Highway standards as of early 2011. A future interchange with I-269 near Byhalia, Mississippi is the western terminus of I-22. The eastern terminus is at an interchange with I-65 in Jefferson County, north of Birmingham.