Interleukin 17 receptor D

IL17RD
Identifiers
Aliases	IL17RD, HH18, IL-17RD, IL17RLM, SEF, interleukin 17 receptor D
External IDs	MGI: 2159727 HomoloGene: 9717 GeneCards: IL17RD
Gene location (Human) Chr. Chromosome 3 (human) Band n/a Start 57,089,982 bp End 57,170,306 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band n/a Start 27,039,001 bp End 27,107,286 bp
Gene ontology Molecular function • interleukin-17 receptor activity Cellular component • cytoplasm • integral component of membrane • Golgi apparatus • membrane • Golgi membrane • plasma • integral component of plasma membrane • nucleoplasm Biological process • MAPK cascade • signal transduction • cytokine-mediated signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	54756	171463
Ensembl	ENSG00000144730	ENSMUSG00000040717
UniProt	Q8NFM7	Q8JZL1
RefSeq (mRNA)	NM_017563 NM_001318864	NM_027265 NM_134437
RefSeq (protein)	NP_001305793 NP_060033	NP_602319
Location (UCSC)	Chr 3: 57.09 – 57.17 Mb	Chr 3: 27.04 – 27.11 Mb
PubMed search

54756

171463

ENSG00000144730

ENSMUSG00000040717

Q8NFM7

Q8JZL1

NM_017563
NM_001318864

NM_027265
NM_134437

NP_001305793
NP_060033

NP_602319

Interleukin 17 receptor D is a protein that in humans is encoded by the IL17RD gene.

This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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