Interleukin 15

IL15

Protein IL15 PDB 2Z3Q.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2XQB, 2Z3Q, 2Z3R, 4GS7

Identifiers

IL15, IL-15, interleukin 15

External IDs

OMIM: 600554 MGI: 103014 HomoloGene: 487 GeneCards: IL15

Gene ontology
Molecular function	• protein binding • cytokine receptor binding • cytokine activity
Cellular component	• nucleus • integral component of plasma membrane • Golgi apparatus • endosome • nucleoplasm • membrane • cell surface • extracellular region • extracellular space • cytoplasm • cytosol • nuclear speck
Biological process	• negative regulation of smooth muscle cell proliferation • cell maturation • extrathymic T cell selection • positive regulation of T cell proliferation • regulation of defense response to virus by host • positive regulation of inflammatory response • response to nutrient levels • positive regulation of protein O-linked glycosylation • positive regulation of interleukin-17 production • hyaluronan metabolic process • positive regulation of natural killer cell differentiation • regulation of T cell differentiation • positive regulation of tissue remodeling • cellular response to vitamin D • lymph node development • natural killer cell differentiation • positive regulation of natural killer cell proliferation • cell-cell signaling • skeletal muscle atrophy • signal transduction • aging • NK T cell proliferation • positive regulation of immune response • inflammatory response • immune response • positive regulation of cell proliferation • tyrosine phosphorylation of STAT protein • interleukin-15-mediated signaling pathway
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE IL15 205992 s at fs.png

PBB GE IL15 217371 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


3600


16168


ENSG00000164136


ENSMUSG00000031712


P40933


P48346

RefSeq (mRNA)


NM_000585 NM_172174 NM_172175


NM_001254747 NM_008357

RefSeq (protein)


NP_000576 NP_751915


NP_001241676.1 NP_032383.1 NP_001241676 NP_032383

Location (UCSC)

Chr 4: 141.64 – 141.73 Mb

Chr 8: 82.33 – 82.4 Mb

PubMed search

2XQB, 2Z3Q, 2Z3R, 4GS7

ENSG00000164136

ENSMUSG00000031712

NM_000585
NM_172174
NM_172175

NM_001254747
NM_008357

NP_000576
NP_751915

NP_001241676.1
NP_032383.1
NP_001241676
NP_032383

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Wikipedia

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