Interleukin-4 receptor

IL4R

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1IAR, 1IRS, 3BPL, 3BPN, 3BPO, 5E4E

Identifiers

Aliases

IL4R, CD124, IL-4RA, IL4RA, Interleukin-4 receptor, interleukin 4 receptor

External IDs

MGI: 105367 HomoloGene: 7784 GeneCards: IL4R

Gene ontology
Molecular function	• signal transducer activity, downstream of receptor • protein binding • cytokine receptor activity • interleukin-4 receptor activity
Cellular component	• integral component of membrane • membrane • receptor complex • integral component of plasma membrane • extracellular region • extracellular space • plasma membrane
Biological process	• cytokine-mediated signaling pathway • immune system process • positive regulation of chemokine secretion • positive regulation of immunoglobulin production • positive regulation of macrophage activation • positive regulation of mast cell degranulation • response to estrogen • production of molecular mediator involved in inflammatory response • positive regulation of myoblast fusion • negative regulation of T-helper 1 cell differentiation • regulation of cell proliferation • immunoglobulin mediated immune response • immune response • positive regulation of T-helper 2 cell differentiation • ovulation • signal transduction • defense response to protozoan • interleukin-4-mediated signaling pathway • response to odorant
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


3566


16190

Ensembl


ENSG00000077238


ENSMUSG00000030748

UniProt


P24394


P16382

RefSeq (mRNA)


NM_000418 NM_001008699 NM_001257406 NM_001257407 NM_001257997


NM_001008700 NM_010557

RefSeq (protein)


NP_000409 NP_001244335 NP_001244336 NP_001244926


NP_001008700

Location (UCSC)

Chr 16: 27.31 – 27.36 Mb

Chr 7: 125.55 – 125.58 Mb

PubMed search

Interleukin-4 receptor alpha chain, N-terminal

interleukin-4 / receptor alpha chain complex

Identifiers

Symbol

IL4Ra_N

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

1IAR, 1IRS, 3BPL, 3BPN, 3BPO, 5E4E

NM_000418
NM_001008699
NM_001257406
NM_001257407
NM_001257997

NM_001008700
NM_010557

NP_000409
NP_001244335
NP_001244336
NP_001244926

...
Wikipedia