Insulin-like growth factor 2 receptor

IGF2R

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1E6F, 1GP0, 1GP3, 1GQB, 1JPL, 1JWG, 1LF8, 2CNJ, 2V5N, 2V5O, 2V5P, 2L29, 2L2A, 2M68, 5IEI, 2M6T

Identifiers

Aliases

IGF2R, CD222, CIMPR, M6P-R, MPR1, MPRI, M6P/MPR 300, CI-M6PR, MPR300, insulin like growth factor 2 receptor

External IDs

OMIM: 147280 MGI: 96435 HomoloGene: 676 GeneCards: IGF2R

Genetically Related Diseases

periodontitis

Gene ontology
Molecular function	• retinoic acid binding • insulin-like growth factor binding • G-protein coupled receptor activity • transporter activity • glycoprotein binding • phosphoprotein binding • insulin-like growth factor-activated receptor activity • insulin-like growth factor II binding • protein binding • mannose binding • identical protein binding • enzyme binding • G-protein alpha-subunit binding • receptor activity
Cellular component	• cytoplasm • integral component of membrane • endosome • late endosome • membrane • focal adhesion • clathrin coat • endocytic vesicle • integral component of plasma membrane • cell surface • lysosomal membrane • trans-Golgi network • early endosome • nuclear envelope lumen • perinuclear region of cytoplasm • trans-Golgi network transport vesicle • lysosome • extracellular exosome • nucleus • trans-Golgi network membrane • transport vesicle • extracellular space • Golgi apparatus • plasma membrane • clathrin-coated vesicle membrane • secretory granule membrane
Biological process	• regulation of apoptotic process • G-protein coupled receptor signaling pathway • response to retinoic acid • post-embryonic development • receptor-mediated endocytosis • animal organ regeneration • spermatogenesis • transport • positive regulation of apoptotic process • liver development • signal transduction • insulin-like growth factor receptor signaling pathway • neutrophil degranulation • membrane organization
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


3482


16004

Ensembl


ENSG00000197081


ENSMUSG00000023830

UniProt


P11717


Q07113

RefSeq (mRNA)


NM_000876


NM_010515

RefSeq (protein)


NP_000867


NP_034645.2 NP_034645

Location (UCSC)

Chr 6: 159.97 – 160.11 Mb

Chr 17: 12.68 – 12.77 Mb

PubMed search

1E6F, 1GP0, 1GP3, 1GQB, 1JPL, 1JWG, 1LF8, 2CNJ, 2V5N, 2V5O, 2V5P, 2L29, 2L2A, 2M68, 5IEI, 2M6T

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