Insulin-like growth factor 2

IGF2

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3KR3, 1IGL, 2L29, 2V5P, 3E4Z

Identifiers

Aliases

IGF2, C11orf43, GRDF, IGF-II, PP9974, insulin like growth factor 2

External IDs

OMIM: 147470 MGI: 96434 HomoloGene: 510 GeneCards: IGF2

Gene ontology
Molecular function	• insulin-like growth factor receptor binding • insulin receptor binding • hormone activity • protein serine/threonine kinase activator activity • receptor activator activity • protein binding • growth factor activity
Cellular component	• plasma membrane • extracellular region • extracellular exosome • platelet alpha granule lumen • extracellular space
Biological process	• regulation of gene expression by genetic imprinting • skeletal system development • cellular protein metabolic process • insulin receptor signaling pathway • positive regulation of protein kinase B signaling • positive regulation of protein phosphorylation • positive regulation of glycogen biosynthetic process • regulation of transcription, DNA-templated • ossification • carbohydrate metabolic process • platelet degranulation • positive regulation of catalytic activity • multicellular organism development • positive regulation of cell proliferation • insulin receptor signaling pathway via phosphatidylinositol 3-kinase • glucose metabolic process • positive regulation of peptidyl-tyrosine phosphorylation • positive regulation of glycogen (starch) synthase activity • positive regulation of insulin receptor signaling pathway • positive regulation of mitotic nuclear division • positive regulation of cell division • positive regulation of MAPK cascade • positive regulation of activated T cell proliferation • positive regulation of receptor activity • positive regulation of protein serine/threonine kinase activity
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


3481


16002

Ensembl


ENSG00000167244


ENSMUSG00000048583

UniProt


P01344


P09535

RefSeq (mRNA)


NM_001291862 NM_000612 NM_001007139 NM_001127598 NM_001291861


NM_001122736 NM_001122737 NM_010514 NM_001315488 NM_001315489

RefSeq (protein)


NP_000603 NP_001007140 NP_001121070 NP_001278790 NP_001278791

NP_001116208.1 NP_001116209.1 NP_001302417.1 NP_001302418.1 NP_001116208
NP_001116209 NP_001302417 NP_001302418 NP_034644

Location (UCSC)

Chr 11: 2.13 – 2.14 Mb

Chr 7: 142.65 – 142.67 Mb

PubMed search

Insulin-like growth factor II E-peptide (somatomedians-A )

Identifiers

Symbol

IGF2_C

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

3KR3, 1IGL, 2L29, 2V5P, 3E4Z

NM_001291862
NM_000612
NM_001007139
NM_001127598
NM_001291861

NM_001122736
NM_001122737
NM_010514
NM_001315488
NM_001315489

NP_000603
NP_001007140
NP_001121070
NP_001278790
NP_001278791

...
Wikipedia