Injectable contraceptives
| Combination of | |
|---|---|
| Estradiol cypionate | Estrogen |
| Medroxyprogesterone acetate | Progestogen |
| Clinical data | |
| Trade names | Lunelle, Cyclofem, others |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| Pregnancy category |
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| Routes of administration |
IM |
| ATC code | |
| Legal status | |
| Legal status |
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Estradiol cypionate/medroxyprogesterone acetate, sold under the brand name Lunelle among others, is form of combined injectable birth control. It contains estradiol cypionate an estrogen and medroxyprogesterone acetate a progestin. It is recommended for short-term use and is given once a month by injection into a muscle.
Common side effects include irregular menstrual periods which typically improves with time. Other side effects include blood clots, headache, hair loss, depression, nausea, and breast pain. Use during pregnancy is not recommended. Use during breastfeeding is likely safe. It works mainly by preventing ovulation.
Estradiol cypionate/medroxyprogesterone acetate came into medical use in 1993 with approval in the United States in 2000. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. It is used in Mexico, Thailand and Indonesia among other countries. It is no longer commercially available in the United States.
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