Illinois Route 146
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| Route information | ||||
| Maintained by IDOT | ||||
| Length: | 92.93 mi (149.56 km) | |||
| Existed: | 1926 – present | |||
| Major junctions | ||||
| West end: |
  Route 34 / Route 74 in East Cape Girardeau
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 US 51 in Anna I-57 in Anna US 45 in Vienna I-24 in Vienna |
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| East end: |
 IL 1 in Cave-in-Rock
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| Location | ||||
| Counties: | Alexander, Union, Johnson, Pope, Hardin | |||
| Highway system | ||||
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Illinois Route 146 (IL 146) is an east–west state highway in the U.S. state of Illinois. It serves the extreme southern region of the state, commonly called Little Egypt or the Illinois Ozarks. IL-146 is 92.93 miles (149.56 km) long. An east–west highway, it serves Hardin County, Pope County, Johnson County, and Union County. These are some of the least-populated counties in Illinois. IL-146 serves two sections of the Shawnee National Forest.
IL-146 generally follows a land route of the Trail of Tears, a trail taken by bands of approximately 9,000 Cherokee who were forced to march through southern Illinois from November 1838 until January 1839 as part of a U.S. government mandated relocation. In 2006, the state of Illinois designated IL-146 as a historic highway and route of the Trail of Tears.
IL-146 intersects with two U.S. Interstate Highways: Interstate 24 at exit 16 near Vienna, and Interstate 57 at exit 30 near Anna.
IL-146 passes through an area of Illinois noted for scenic beauty and significant tourist visitation. State-operated parks and recreation areas on or adjacent to IL-146 include, from west to east:
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