"I Can't Live with You" is a song by the British rock group Queen. It was released as a promo single from their 1991 album Innuendo. The single was released by Hollywood Records in the United States only, peaking at #28 on the Mainstream Rock Chart.

The song was written by Brian May but credited to all four members of Queen. "I Can't Live with You" was originally written for May's solo album. He gave it to the band since all three other members of Queen were fond of the track. Drums were programmed on synth by May, and the keyboard-pads were added by the producer David Richards.

For this promotional single, American producer Brian Malouf remixed the original album track. The remix was titled "I Can't Live with You (Malouf Mix)". Despite the promo sleeve only displaying one track, there are two on the single, the other being "I Can't Live with You (Malouf Mix Edit)".

The Malouf Mix uses slightly different lead vocal tracks by Freddie Mercury, louder and tighter harmony tracks, and reprogrammed synth drums, resulting in a much more punchy and "over the top" poppy version than included on the album.

An alternative version of this song appeared on the 1997 compilation album Queen Rocks, billed as the "'97 Rocks Retake". it was said to be more along the lines of how May and Taylor originally wanted the track to sound, with a harder, guitar-driven rock edge. The original versions vocal was used in this retake.

It was among the last songs recorded by Freddie Mercury, who died within a year of the album's release.

In August 1991, May was interviewed by Guitar World where he spoke of the song. "As time goes by I find I'm more concerned with the lyrics than ever. A lot of people say you can only create when you're in pain. But when I was really in pain, I couldn't create anything. I couldn't even get out of bed. When you're climbing out and beginning to get things in the right boxes again, that's when you can put it into music. There's quite a bit of that sort of thing on this album. There's some in 'I Can't Live with You'; it's very personal, but I tried not to make it autobiographical because that narrows things too much. I tried to express it in a form that everyone can relate to."

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