ITSN1

ITSN1

Protein ITSN1 PDB 1ki1.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1KI1, 2KGR, 2KHN, 3QBV, 4IIM

Identifiers

ITSN1, ITSN, SH3D1A, SH3P17, intersectin 1

External IDs

MGI: 1338069 HomoloGene: 2277 GeneCards: ITSN1

Gene ontology
Molecular function	• calcium ion binding • metal ion binding • protein binding • kinase activator activity • protein complex scaffold activity • proline-rich region binding • guanyl-nucleotide exchange factor activity • Rho guanyl-nucleotide exchange factor activity
Cellular component	• cytosol • cell projection • membrane • plasma membrane • endocytic vesicle • synapse • cell junction • neuron projection • clathrin-coated pit • endomembrane system • lamellipodium
Biological process	• negative regulation of neuron apoptotic process • positive regulation of protein kinase B signaling • intracellular signal transduction • endocytosis • ephrin receptor signaling pathway • synaptic vesicle endocytosis • positive regulation of apoptotic process • positive regulation of phosphorylation • regulation of Rho protein signal transduction • regulation of small GTPase mediated signal transduction • small GTPase mediated signal transduction • positive regulation of GTPase activity • membrane organization • viral process
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE ITSN1 207322 at fs.png

PBB GE ITSN1 35776 at fs.png

PBB GE ITSN1 209297 at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


6453


16443


ENSG00000205726


ENSMUSG00000022957


Q15811 Q6J334


Q9Z0R4

RefSeq (mRNA)

NM_001001132 NM_003024 NM_001331008 NM_001331009 NM_001331010
NM_001331011 NM_001331012


NM_001110275 NM_001110276 NM_010587

RefSeq (protein)

NP_001001132 NP_001317937 NP_001317938 NP_001317939 NP_001317940
NP_001317941 NP_003015


NP_001103745 NP_001103746 NP_034717

Location (UCSC)

Chr 21: 33.64 – 33.9 Mb

Chr 16: 91.73 – 91.92 Mb

PubMed search

1KI1, 2KGR, 2KHN, 3QBV, 4IIM

ENSG00000205726

ENSMUSG00000022957

NM_001331011
NM_001331012

NM_001110275
NM_001110276
NM_010587

NP_001317941
NP_003015

NP_001103745
NP_001103746
NP_034717

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Wikipedia

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