ISG20

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1WLJ

Identifiers

ISG20, CD25, HEM45, interferon stimulated exonuclease gene 20kDa, interferon stimulated exonuclease gene 20

External IDs

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• 3'-5'-exoribonuclease activity • single-stranded DNA 3'-5' exodeoxyribonuclease activity • exoribonuclease II activity • metal ion binding • U3 snoRNA binding • U2 snRNA binding • RNA binding • nucleic acid binding • U1 snRNA binding • nuclease activity • exonuclease activity • hydrolase activity
Cellular component	• cytoplasm • Cajal body • PML body • nucleoplasm • nucleolus • nucleus
Biological process	• immune system process • response to virus • RNA catabolic process • negative regulation of viral genome replication • DNA catabolic process, exonucleolytic • defense response to virus • type I interferon signaling pathway • rRNA processing • innate immune response • cell proliferation • RNA phosphodiester bond hydrolysis, exonucleolytic
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


3669


57444


ENSG00000172183


ENSMUSG00000039236


Q96AZ6


Q9JL16

RefSeq (mRNA)

NM_001303233 NM_001303234 NM_001303235 NM_001303236 NM_001303237
NM_002201


NM_001113527 NM_001291220 NM_001291221 NM_020583

RefSeq (protein)

NP_001290162 NP_001290163 NP_001290164 NP_001290165 NP_001290166
NP_002192


NP_001106999 NP_001278149 NP_001278150 NP_065608

Location (UCSC)

PubMed search

Interferon-stimulated gene 20 kDa protein is a protein that in humans is encoded by the ISG20 gene.