IL2RA

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1Z92, 2B5I, 2ERJ, 3IU3, 3NFP

Identifiers

IL2RA, CD25, IDDM10, IL2R, TCGFR, p55, IMD41, interleukin 2 receptor subunit alpha

External IDs

Gene ontology
Molecular function	• drug binding • Ras guanyl-nucleotide exchange factor activity • interleukin-2 receptor activity • interleukin-2 binding
Cellular component	• integral component of membrane • membrane • plasma membrane • cell surface • external side of plasma membrane • intracellular
Biological process	• Notch signaling pathway • positive regulation of T cell differentiation • regulation of T cell tolerance induction • inflammatory response to antigenic stimulus • negative regulation of defense response to virus • immune system process • activation-induced cell death of T cells • negative regulation of lymphocyte proliferation • MAPK cascade • T cell homeostasis • regulation of T cell homeostatic proliferation • cell surface receptor signaling pathway • negative regulation of T cell proliferation • negative regulation of immune response • immune response • interleukin-2-mediated signaling pathway • positive regulation of T cell proliferation • cell proliferation • inflammatory response • negative regulation of inflammatory response • positive regulation of activated T cell proliferation • apoptotic process • positive regulation of GTPase activity
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


3559


16184


ENSG00000134460


ENSMUSG00000026770


P01589


P01590

RefSeq (mRNA)


NM_000417 NM_001308242 NM_001308243


NM_008367

RefSeq (protein)


NP_000408 NP_001295171 NP_001295172


NP_032393.3 NP_032393

Location (UCSC)

PubMed search

Interleukin-2 receptor alpha chain (also called CD25) is a protein that in humans is encoded by the IL2RA gene.