IL13RA2 | |||||||||||||||||
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Identifiers | |||||||||||||||||
Aliases | IL13RA2, CD213A2, CT19, IL-13R, IL13BP, interleukin 13 receptor subunit alpha 2 | ||||||||||||||||
External IDs | MGI: 1277954 HomoloGene: 534 GeneCards: IL13RA2 | ||||||||||||||||
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RNA expression pattern | |||||||||||||||||
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More reference expression data | |||||||||||||||||
Orthologs | |||||||||||||||||
Species | Human | Mouse | |||||||||||||||
Entrez |
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Ensembl |
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UniProt |
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RefSeq (mRNA) |
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RefSeq (protein) |
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Location (UCSC) | Chr X: 115 – 115.02 Mb | Chr X: 147.38 – 147.43 Mb | |||||||||||||||
PubMed search | |||||||||||||||||
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NP_001292988.1
NP_032382.1
NP_001292988
NP_032382
Interleukin-13 receptor subunit alpha-2 (IL-13Rα2), also known as CD213A2 (cluster of differentiation 213A2), is a membrane bound protein that in humans is encoded by the IL13RA2 gene.
IL-13Rα2 is closely related to IL-13Rα1, a subunit of the interleukin-13 receptor complex. This protein binds IL13 with high affinity, but lacks any significant cytoplasmic domain, and does not appear to function as a signal mediator. It is, however able to regulate the effects of both IL-13 and IL-4, despite the fact it is unable to bind directly to the latter. It is also reported to play a role in the internalization of IL13.