IGFBP5

IGFBP5
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1BOE, 1H59
Identifiers
Aliases	IGFBP5, IBP5, insulin like growth factor binding protein 5
External IDs	MGI: 96440 HomoloGene: 56489 GeneCards: IGFBP5
Gene ontology Molecular function • fibronectin binding • insulin-like growth factor binding • growth factor binding • insulin-like growth factor I binding • insulin-like growth factor II binding • protein binding Cellular component • insulin-like growth factor ternary complex • extracellular region • insulin-like growth factor binding protein complex • endoplasmic reticulum lumen Biological process • cellular protein metabolic process • negative regulation of smooth muscle cell proliferation • negative regulation of translation • positive regulation of protein kinase B signaling • intracellular signal transduction • negative regulation of growth • glucose homeostasis • female pregnancy • cellular response to organic cyclic compound • negative regulation of smooth muscle cell migration • negative regulation of osteoblast differentiation • regulation of glucose metabolic process • negative regulation of cell migration • positive regulation of insulin-like growth factor receptor signaling pathway • regulation of cell growth • osteoblast differentiation • response to growth hormone • glucose metabolic process • negative regulation of insulin-like growth factor receptor signaling pathway • hair follicle morphogenesis • regulation of growth • negative regulation of muscle tissue development • striated muscle cell differentiation • lung alveolus development • negative regulation of skeletal muscle hypertrophy • type B pancreatic cell proliferation • cellular response to cAMP • signal transduction • mammary gland involution • aging • post-translational protein modification Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3488	16011
Ensembl	ENSG00000115461	ENSMUSG00000026185
UniProt	P24593	Q07079
RefSeq (mRNA)	NM_000599	NM_010518
RefSeq (protein)	NP_000590	NP_034648
Location (UCSC)	Chr 2: 216.67 – 216.7 Mb	Chr 1: 72.86 – 72.87 Mb
PubMed search

1BOE, 1H59

3488

16011

ENSG00000115461

ENSMUSG00000026185

P24593

Q07079

NM_000599

NM_010518

NP_000590

NP_034648

Insulin-like growth factor-binding protein 5 is a protein that in humans is encoded by the IGFBP5 gene.

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