IDH1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1T09, 1T0L, 3INM, 3MAP, 3MAR, 3MAS, 4I3K, 4I3L, 4KZO, 4L03, 4L04, 4L06, 4UMX, 4UMY, 4XRX, 5DE1, 4XS3, 5K10, 5K11

Identifiers

IDH1, HEL-216, HEL-S-26, IDCD, IDH, IDP, IDPC, PICD, isocitrate dehydrogenase (NADP(+)) 1, cytosolic

External IDs

Gene ontology
Molecular function	• magnesium ion binding • protein homodimerization activity • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor • receptor binding • isocitrate dehydrogenase (NADP+) activity • oxidoreductase activity • NAD binding • isocitrate dehydrogenase activity • NADP binding • metal ion binding • (R)-2-hydroxyglutarate dehydrogenase activity • cadherin binding
Cellular component	• peroxisome • cytosol • extracellular exosome • peroxisomal matrix • cytoplasm • mitochondrion • extracellular region • secretory granule lumen • tertiary granule lumen • ficolin-1-rich granule lumen
Biological process	• female gonad development • NADPH regeneration • response to oxidative stress • response to organic cyclic compound • response to steroid hormone • 2-oxoglutarate metabolic process • regulation of phospholipid catabolic process • isocitrate metabolic process • glyoxylate cycle • tricarboxylic acid cycle • regulation of phospholipid biosynthetic process • glutathione metabolic process • oxidation-reduction process • neutrophil degranulation
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


3417


15926


ENSG00000138413


ENSMUSG00000025950


O75874


O88844

RefSeq (mRNA)


NM_005896 NM_001282386 NM_001282387


NM_001111320 NM_010497

RefSeq (protein)


NP_001269315 NP_001269316 NP_005887


NP_001104790.1 NP_034627.3 NP_001104790 NP_034627

Location (UCSC)

PubMed search