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Hyperchloremic acidosis

Hyperchloremic acidosis
Classification and external resources
Specialty endocrinology
ICD-10 E87.2
ICD-9-CM 276.2
eMedicine med/1071
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Hyperchloremic acidosis is a form of metabolic acidosis associated with a normal anion gap, a decrease in plasma bicarbonate concentration, and an increase in plasma chloride concentration (see anion gap for a fuller explanation). Although plasma anion gap is normal, this condition is often associated with an increased urine anion gap, due to the kidney's inability to secrete ammonia.

In general, the cause of a hyperchloremic metabolic acidosis is a loss of base, either a gastrointestinal loss or a renal loss.


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