Hydroxymethylbilane synthase

HMBS

Protein HMBS PDB 3ECR.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3ECR, 3EQ1

Identifiers

HMBS, PBG-D, PBGD, PORC, UPS, hydroxymethylbilane synthase

External IDs

OMIM: 609806 MGI: 96112 HomoloGene: 158 GeneCards: HMBS

Gene location (Human)

Chr.	Chromosome 11 (human)

Band	11q23.3	Start	119,084,866 bp
Band	11q23.3	End	119,093,549 bp

Gene location (Mouse)

Chr.	Chromosome 9 (mouse)

Band	9 A5.2\|9 24.84 cM	Start	44,336,339 bp
Band	9 A5.2\|9 24.84 cM	End	44,344,228 bp

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• transferase activity • hydroxymethylbilane synthase activity
Cellular component	• cytosol • cytoplasm
Biological process	• protoporphyrinogen IX biosynthetic process • tetrapyrrole biosynthetic process • porphyrin-containing compound biosynthetic process • peptidyl-pyrromethane cofactor linkage • heme biosynthetic process
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


3145


15288


ENSG00000256269 ENSG00000281702


ENSMUSG00000032126


P08397


P22907

RefSeq (mRNA)


NM_000190 NM_001024382 NM_001258208 NM_001258209


NM_001110251 NM_013551

RefSeq (protein)


NP_000181 NP_001019553 NP_001245137 NP_001245138


NP_001103721 NP_038579

Location (UCSC)

Chr 11: 119.08 – 119.09 Mb

Chr 11: 44.34 – 44.34 Mb

PubMed search

ENSG00000256269
ENSG00000281702

ENSMUSG00000032126

NM_000190
NM_001024382
NM_001258208
NM_001258209

NM_001110251
NM_013551

NP_000181
NP_001019553
NP_001245137
NP_001245138

NP_001103721
NP_038579

...
Wikipedia

...