Hlučín Region (Czech: Hlučínsko (familiarly Prajzsko), German: Hultschiner Ländchen, Polish: Kraik hulczyński) is a historically significant part of Czech Silesia, today a part of the Moravian-Silesian Region in the Czech Republic, named after its largest town Hlučín. Its area is 316.9 square kilometres (122.4 sq mi) and in 2001 it had about 73,914 inhabitants.
Archaeological finds suggest that the area was inhabited since 4500 - 2500 BC.
The medieval bishoprics of Olomouc and Wrocław both were tried to control it. In the end, Olomouc won the dispute and the area became part of the March of Moravia. In 1269, Hlučín belonged to the lands that were split off Moravia by King Ottokar II of Bohemia as the Duchy of Opava, ruled by his illegitimate son Duke Nicholas I. Differences in culture, traditions and economical development from the rest of Moravia grew during the time, mainly caused by Germanisation in the course of the Ostsiedlung. From 1526 onwards, the Duchy of Troppau together with the Lands of the Bohemian Crown was part of the Habsburg Monarchy.
The history of Hlučínsko as an entity began with the Treaty of Breslau signed on 11 June 1742 between King Frederick II of Prussia and Empress Maria Theresa of Austria. In 1740, Prussia started the First Silesian War and conquered most of Silesia. According to the terms of the treaty, the Duchy of Troppau was partitioned: while the lands south of the Opava river remained with Austrian Silesia, the northern part around Hlučín fell to Prussia and was incorporated into the Province of Silesia in 1815.