Higashi-Kanda (東神田?) is a district of Chiyoda, Tokyo, Japan, consisting of 1- to 3-chōme. As of April 1, 2007, its population is 1,718. Its postal code is 101-0031.
Higashi-Kanda is located on the northeastern part of Chiyoda. It borders Asakusabashi 4-chōme, Taitō to the north; Asakusabashi 1-chōme, Taitō and Nihonbashi-Bakurochō, Chūō to the east; Nihonbashi-Kodenmachō, Chūō to the south; and , Chiyoda to the west.
The Kanda River runs between Higashi-Kanda 2-chōme and 3-chōme.
Higashi-Kanda 1-chōme is home to the Tokyo Metropolitan Institute Hitotsubashi High School.