Hermann Mucke (bioscientist)

Hermann A. M. Mucke (born 4 September 1955) is an Austrian bioscientist with a peer-review publishing record in the fields of molecular biology, neuropsychiatry, cardiology and ophthalmology, mostly from the perspective of drug development. He is also a management consultant and entrepreneur working and publishing in biopharmaceutical strategic knowledge management, intellectual property management, and life science technology assessment.

Hermann Mucke attended the University of Vienna where he obtained his master and Ph.D. degrees in biochemistry. This earliest plant molecular biology phase of Mucke's work concerned the characterization and partial sequencing of the Cyanophora cyanelle genome, believed to resemble early stages of chloroplast evolution according to the endosymbiotic theory.

After leaving the university Mucke became executive director of research and development at an Austrian pharmaceutical company. He developed an indirect immunofluorescence assay for the detection of antibodies to the human immunodeficiency virus in human body fluids which was approved under the name Fluorognost(TM) HIV-1 by the U.S. FDA approval on 5 February 1992. A human T-lymphotropic virus antibody test, developed by Mucke's team but never marketed, served to demonstrate the first evidence of retrovirus-like serological reactivity in patients with the myelodysplastic syndrome, a finding that meanwhile has been corroborated on the genomic level.

In 1994 Mucke developed a new research focus in neuropsychiatry, initially with a focus on Alzheimer's disease and related neurodegenerative diseases. He directed an R&D program for galantamine derivatives. Soon thereafter he began to cooperate with various pharmaceutical intelligence providers and publishers in the United States and the United Kingdom, both as an author and as a contributing editor.

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