Hermann Müller (21 October 1850 in Tägerwilen, Thurgau, Switzerland – 18 January 1927, in Wädenswil, Zurich), was a Swiss botanist, plant physiologist, oenologist and grape breeder. He called himself Müller-Thurgau, taking the name of his home canton.
Hermann Müller was born to Konrad Müller, a master baker and vintner, and his wife Maria Egloff, the daughter of Karl Anton Egloff, a wine merchant of Oestrich, Hessen. He attended the Lehrerseminar Kreuzlingen (Kreuzlingen Teachers College) (1869-70). He taught in Stein am Rhein (1870-72) while studying at the Polytechnikum Zürich (1872 graduate). He then attended the University of Würzburg for graduate studies under Julius von Sachs, was awarded his PdD in 1874 and stayed some time as Sachs' assistant. During the years 1876−1890 he worked at the Prussian Institute for Horticulture and Viticulture (Königlich Preussische Lehranstalt für Obst- und Weinbau) in Geisenheim, Rheingau where he led its experimental station for plant physiology.
In 1891 he returned to Switzerland as director of the newly created Experimental Station and School for Horticulture and Viticulture (Versuchsstation und Schule für Obst-, Wein- und Gartenbau) in Wädenswil, where he stayed until his 1924 retirement. From 1902, he was also connected to Polytechnikum Zürich as professor of botany.
He worked on teams which investigated fertility of the vine, vine diseases, and malolactic fermentation in wine.
In 1890, he was made an honorary member of the German Viticultural Association and in 1920 he received an honorary doctorate from the University of Bern.