Henry O'Brien, 5th Earl of Thomond

Henry O'Brien, 5th Earl of Thomond (1588 – 26 July 1639) was an Irish peer, styled Lord Ibrickane until 1624.

O'Brien was the son of Donogh O'Brien, 4th Earl of Thomond and Elisabeth FitzGerald. He married, on July 13, 1608, Mary Brereton, daughter of William Brereton, 1st Baron Brereton and Margaret Savage, and together they had 5 daughters:

O'Brien died in 1639, and was succeeded in his peerages by his brother Barnabas O'Brien, 6th Earl of Thomond.