Hendrik (Hendrikus) van de Sande Bakhuyzen (2 January 1795 The Hague – 12 December 1860, The Hague) was a 19th Century Dutch landscape painter and art teacher. He was a prominent contributor to the Romantic period in Dutch art and his students and children founded the art movement known as the Hague School. Like his contemporaries Edward Williams, Jacob Maris, and Jozef Israels, he was part of a family of prominent painters, including son Julius van de Sande Bakhuyzen, daughter Gerardina Jacoba van de Sande Bakhuyzen, and nephew Alexander Hieronymus Bakhuyzen.
He was born under the name Hendrikus Bakhuyzen in the Hague in 1795, the son of prominent publisher Gerrit Bakhuysen (1758–1843) and Jacoba van de Sande (1757–1815). In 1819 he obtained a Royal Decree granting legal permission to add his late mother's surname to his own and became known as Hendrikus van de Sande Bakhuyzen. His wife was Sophia Wilhelmine Kiehl (1804–1881). He lived principally in The Hague in the Netherlands. He died on December 12, 1860. His son, Julius van de Sande Bakhuyzen (1835–1925), became a well-known landscape painter as well. His daughter, Gerardine Jacoba van de Sande Bakhuyzen (1826–1895), was a painter of still life, flowers, and fruit. His son Henricus Gerardus van de Sande Bakhuyzen (1838–1923) became a prominent astronomer, member of the Royal Netherlands Academy of Arts and Sciences, and director of the Leiden Observatory. His son Ernest-Frederich van de Sande Bakhuyzen was also an astronomer at the Leiden Observatory.