HBZ | |||||||||||||||||
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Identifiers | |||||||||||||||||
Aliases | HBZ, HBZ-T1, HBZ1, hemoglobin subunit zeta | ||||||||||||||||
External IDs | MGI: 96019 HomoloGene: 110705 GeneCards: HBZ | ||||||||||||||||
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RNA expression pattern | |||||||||||||||||
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Orthologs | |||||||||||||||||
Species | Human | Mouse | |||||||||||||||
Entrez |
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Ensembl |
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UniProt |
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RefSeq (mRNA) |
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RefSeq (protein) |
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Location (UCSC) | Chr 16: 0.15 – 0.15 Mb | Chr 11: 32.28 – 32.28 Mb | |||||||||||||||
PubMed search | |||||||||||||||||
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Hemoglobin subunit zeta is a protein that in humans is encoded by the HBZ gene.
Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta1 - 3'.