Hemochorial placentation

Placentation
Placentation resulting from cleavage at various gestational ages
Details
Latin	placentatio
Anatomical terminology []

In biology, placentation refers to the formation, type and structure, or arrangement of placentas. The function of placentation is to transfer nutrients from maternal tissue to a growing embryo. Placentation is best known in pregnant female mammals (eutheria), but also occurs in other animals, eggs (yolk sac placentation) and flowering plants.

In placental mammals, the placenta forms after the embryo implants into the wall of the uterus. The developing fetus is connected to it via an umbilical cord. Animal placentas are classified based on the number of tissues separating the maternal from the fetal blood. The placentation types found in animals are:

In this type of placentation, the chorionic villi are in contact with the endothelium of maternal blood vessels. (e.g. in most carnivores like cats and dogs)

Chorionic villi, growing into the apertures of uterine glands ( epithelium). (e.g. in ruminants, horses, whales, lower primates)

In hemochorial placentation maternal blood comes in direct contact with the fetal chorion, which it does not in the other two types. It may avail for more efficient transfer of nutrients etc., but is also more challenging for the systems of gestational immune tolerance to avoid rejection of the fetus.

During pregnancy, placentation is the formation and growth of the placenta inside the uterus. It occurs after the implantation of the embryo into the uterine wall and involves the remodeling of blood vessels in order to supply the needed amount of blood. In humans, placentation takes place 7–8 days after fertilization.