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Hemangiopericytoma

Hemangiopericytoma
Skin Tumors-P1120982.JPG
Haemangiopericytoma, Gomori methenamine silver stain
Classification and external resources
Specialty oncology, rheumatology
ICD-10 C49 (ILDS C49.M20)
ICD-O M9150/1
DiseasesDB 29249
eMedicine orthoped/500
MeSH D006393
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A hemangiopericytoma (HPC) is a type of soft tissue sarcoma that originates in the pericytes in the walls of capillaries. When inside the nervous system, although not strictly a meningioma tumor, it is a meningeal tumor with a special aggressive behavior. It was first characterized in 1942.

Hemangiopericytoma located in the cerebral cavity is an aggressive tumor of the Mesenchyme with oval nuclei with scant cytoplasm. "There is dense intercellular reticulin staining. Tumor cells can be fibroblastic, myxoid, or pericytic. These tumors, in contrast to meningiomas, do not stain with epithelial membrane antigen. They have a grade 2 or 3 biological behavior, and need to be distinguished from benign meningiomas because of their high rate of recurrence (68.2%) and metastases (Maier et al. 1992; Kleihues et al. 1993 )."

Depending on the grade of the sarcoma, it is treated with surgery,chemotherapy and/or radiotherapy.

The word hemangiopericytoma comes from the ancient Greek words: (combining form of Ancient Greek αἷμα, haîma, “blood”), (means blood vessel), , (prefix meaning “about” or “around”, “enclosing” or “surrounding”, and “near”, appearing in loanwords from Greek; and -cytoma (refers to the cells surrounding the blood vessel walls).

Schiariti, M; Goetz, P; El-Maghraby, H; Tailor, J; Kitchen, N (Mar 2011). "Hemangiopericytoma: long-term outcome revisited. Clinical article.". Journal of Neurosurgery. 114 (3): 747–55. doi:10.3171/2010.6.JNS091660. PMID 20672899. 


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