"Heart Full of Soul" is a song recorded by English rock group the Yardbirds in 1965. Written by Graham Gouldman, it was the Yardbirds' first single after Jeff Beck replaced Eric Clapton as lead guitarist. Released only three months after "For Your Love", "Heart Full of Soul" reached the top ten on the charts in the United Kingdom and the United States.

The Yardbirds' first recorded the song with an Indian sitar player performing the distinctive instrumental figures. However, the group was dissatisfied with the results. Consequently, Beck developed the part on electric guitar using a fuzz box distortion unit. Music writers have described his contribution as introducing Indian-influenced guitar stylings to rock music.

As one of the Yardbirds' most popular songs, it was frequently performed in concert. There are a number of live recordings, the earliest of which feature Beck, while later ones feature guitarist Jimmy Page. "Heart Full of Soul" appears on several of the group's compilations and renditions have been recorded by other musicians.

Guitarist Eric Clapton left the Yardbirds in March 1965 because of a perceived shift in musical direction. Inspired in part by Jeff Beck, who replaced Clapton, the group began to experiment with different musical styles. Beck had more varied influences and used electronically enhanced guitar effects, such as fuzz and feedback, which he brought to the group's sound. When preparing for a follow-up single to their first record chart hit, "For Your Love", the song's writer Graham Gouldman provided a demo for a new song. Music critic Richie Unterberger described Gouldman as "a genius at effectively alternating tempos and major/minor modes", which are used in "Heart Full of Soul". The shift in tempo and use of double-time was also a feature of the Yardbirds' live performances and was known as a "rave up".

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