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Haplogroup R-M124 (Y-DNA)

Haplogroup R2a
R2, Y-DNA haplogroup.jpg
Possible time of origin 12,000 years BP
Possible place of origin South Asia or Central Asia
Ancestor R-M479
Descendants R-M124*, R-L295, R-L263, R-L1069
Defining mutations M124, P249, P267, L266

Haplogroup R2a, or haplogroup R-M124, is a Y-chromosome haplogroup characterized by genetic markers M124, P249, P267, L266, and is mainly found in South Asia, parts of Central and West Asia.

Haplogoup R2a is also known as haplogroup R-M124. The first reference to the newly defined haplogroup, "R-M124", was on the 25th of August 2010.

Before the publication of the 2005 Y-Chromosome Phylogenetic Tree, Haplogroup R-M124 was known as Haplogroup P1 and formerly thought to be a sister clade of Haplogroup R rather than derived from it.

At least 90% of R-M124 individuals are located in the Indian sub-continent. It is also reported in Caucasus and Central Asia at lower frequency..

According to Sengupta et al. (2006),

uncertainty neutralizes previous conclusions that the intrusion of HGs R1a1 and R2 [Now R-M124] from the northwest in Dravidian-speaking southern tribes is attributable to a single recent event. Rather, these HGs contain considerable demographic complexity, as implied by their high haplotype diversity. Specifically, they could have actually arrived in southern India from a southwestern Asian source region multiple times, with some episodes considerably earlier than others.

 Paragroup R-M124*

 Haplogroup R-L295

 Haplogroup R-L263

 Haplogroup R-L1069

Paragroup is a term used in population genetics to describe lineages within a haplogroup that are not defined by any additional unique markers. They are typically represented by an asterisk (*) placed after the main haplogroup.

Y-chromosomes which are positive to the M124, P249, P267, and L266 SNPs and negative to the L295, L263, and L1069 SNPs, are categorized as belonging to Paragroup R-M124*.


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