Haplogroup E (mtDNA)

Haplogroup E
Possible time of origin	16,400 to 39,000 YBP
Possible place of origin	Indonesia or Taiwan
Ancestor	M9
Descendants	E1, E2
Defining mutations	3027, 3705, 7598, 13626, 16390

In , haplogroup E is a typical for the Malay Archipelago. It is a subgroup of haplogroup M9.

It is believed to have arisen in Northeast Sundaland or around Sulawesi and Sulu Seas. On the other hand, it might be related with the Austronesian languages expansion from Taiwan to Insulinde, indicating a common origin of the populations of insular Southeast Asia and suggesting a prevalence in the Taiwanese aboriginal gene pool (mainly E with B4, B5a, F1a, F3b and M7) of its initial settlers.

Haplogroup E is a subclade of Haplogroup M9, which is the most frequently occurring mtDNA haplogroup among modern Tibetans of Xizang.

Haplogroup E has a Southeast Asian distribution. In particular, it is found among speakers of Austronesian languages, and it is rare even in Southeast Asia among members of other language families. It has been detected in populations of Taiwan, the Philippines, Indonesia, Malaysia (including Sabah of Borneo, but not the Orang Asli of peninsular Malaysia), coastal Papua New Guinea, and especially in the Chamorros of the Mariana Islands.

This phylogenetic tree of haplogroup E subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation and subsequent published research.

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