Hantavirus hemorrhagic fever with renal syndrome
| Hantavirus | |
|---|---|
 |
|
| Transmission electron micrograph of the Sin Nombre Hantavirus | |
| Virus classification | |
| Group: | Group V ((−)ssRNA) |
| Order: | Unassigned |
| Family: | Bunyaviridae |
| Genus: | Hantavirus |
| Type species | |
|
Hantaan virus |
|
| Species | |
|
Asama virus |
|
Asama virus
Gou virus
Hantaan River virus
Dobrava-Belgrade virus
Saaremaa virus
Seoul virus
Puumala virus
Serang virus
Thailand virus
Thottapalayam virus
Nova virus
Hantavirus hemorrhagic fever with renal syndrome (HFRS) is a group of clinically similar illnesses caused by species of hantaviruses from the family Bunyaviridae. It is also known as Korean hemorrhagic fever, epidemic hemorrhagic fever, and nephropathis epidemica. The species that cause HFRS include Hantaan River virus, Dobrava-Belgrade, Saaremaa, Seoul, Puumala and other hantaviruses. It is found in Europe, Asia, and Africa. Of these species, Hantaan River virus and Dobrava-Belgrade virus cause the most severe form of the syndrome and have the highest morbidity rates.
Both hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) appear to be immunopathologic, and inflammatory mediators are important in causing the clinical manifestations.
Symptoms of HFRS usually develop within 1 to 2 weeks after exposure to infectious material, but in rare cases, they may take up to 8 weeks to develop. Initial symptoms begin suddenly and include intense headaches, back and abdominal pain, fever, chills, nausea, and blurred vision. Individuals may have flushing of the face, inflammation or redness of the eyes, or a rash. Later symptoms can include low blood pressure, acute shock, vascular leakage, and acute kidney failure, which can cause severe fluid overload.
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Wikipedia