HNRPH1

HNRNPH1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2LXU

Identifiers

Aliases

HNRNPH1, HNRPH, HNRPH1, hnRNPH, heterogeneous nuclear ribonucleoprotein H1 (H)

External IDs

MGI: 1891925 HomoloGene: 31318 GeneCards: HNRNPH1

Gene ontology
Molecular function	• nucleic acid binding • protein binding • RNA binding • poly(U) RNA binding
Cellular component	• catalytic step 2 spliceosome • spliceosomal complex • intracellular ribonucleoprotein complex • membrane • nucleoplasm • cytosol • nucleus
Biological process	• mRNA splicing, via spliceosome • regulation of RNA splicing • mRNA processing • RNA processing • gene expression • RNA splicing • fibroblast growth factor receptor signaling pathway
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


3187


59013

Ensembl


ENSG00000169045


ENSMUSG00000007850

UniProt


P31943


O35737

RefSeq (mRNA)


NM_001257293 NM_005520


NM_021510 NM_001347487

RefSeq (protein)


NP_001244222 NP_005511


NP_067485.1 NP_001334416 NP_067485

Location (UCSC)

Chr 5: 179.61 – 179.63 Mb

Chr 11: 50.38 – 50.39 Mb

PubMed search

NM_001257293
NM_005520

NM_021510
NM_001347487

NP_001244222
NP_005511

NP_067485.1
NP_001334416
NP_067485

Heterogeneous nuclear ribonucleoprotein H is a protein that in humans is encoded by the HNRNPH1 gene.

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPF. This gene is thought to be potentially involved in hereditary lymphedema type I phenotype.

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