HLA-DRA

HLA-DRA
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1A6A, 1AQD, 1BX2, 1D5M, 1D5X, 1D5Z, 1D6E, 1DLH, 1FV1, 1FYT, 1H15, 1HXY, 1J8H, 1JWM, 1JWS, 1JWU, 1KG0, 1KLG, 1KLU, 1LO5, 1PYW, 1R5I, 1SEB, 1SJE, 1SJH, 1T5W, 1T5X, 1YMM, 1ZGL, 2FSE, 2G9H, 2IAM, 2IAN, 2ICW, 2IPK, 2OJE, 2Q6W, 2WBJ, 2XN9, 3C5J, 3L6F, 3O6F, 3PDO, 3PGC, 3PGD, 3QXA, 3QXD, 3S4S, 3S5L, 3T0E, 4AEN, 4AH2, 4E41, 4FQX, 4GBX, 4H1L, 4C56, 4H25, 4H26, 4I5B, 4IS6, 4MCY, 4MCZ, 4MD0, 4MD4, 4MD5, 4MDI, 4MDJ, 4OV5, 4Y19, 4Y1A, 4X5X, 4X5W
Identifiers
Aliases	HLA-DRA, HLA-DRA1, MLRW, major histocompatibility complex, class II, DR alpha
External IDs	OMIM: 142860 MGI: 95900 HomoloGene: 7751 GeneCards: HLA-DRA
Gene location (Human) Chr. Chromosome 6 (human) Band No data available Start 32,439,842 bp End 32,445,046 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • peptide antigen binding • MHC class II receptor activity • MHC class II protein complex binding • protein binding Cellular component • integral component of membrane • endocytic vesicle membrane • clathrin-coated endocytic vesicle membrane • endosome • Golgi apparatus • trans-Golgi network membrane • endoplasmic reticulum membrane • membrane • late endosome membrane • Golgi membrane • plasma membrane • transport vesicle membrane • integral component of plasma membrane • cell surface • lysosomal membrane • endoplasmic reticulum • ER to Golgi transport vesicle membrane • lysosome • integral component of lumenal side of endoplasmic reticulum membrane • endosome membrane • extracellular exosome • MHC class II protein complex Biological process • antigen processing and presentation • polysaccharide assembly with MHC class II protein complex • antigen processing and presentation of exogenous peptide antigen via MHC class II • cognition • interferon-gamma-mediated signaling pathway • immune system process • T cell costimulation • antigen processing and presentation of peptide or polysaccharide antigen via MHC class II • immune response • peptide antigen assembly with MHC class II protein complex • viral process • T cell receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	3122	100504404
Ensembl	ENSG00000277263 ENSG00000206308 ENSG00000228987 ENSG00000230726 ENSG00000204287 ENSG00000227993 ENSG00000226260 ENSG00000234794	n/a
UniProt	P01903	P14439 P01904
RefSeq (mRNA)	NM_019111	NM_010381
RefSeq (protein)	NP_061984	NP_034511
Location (UCSC)	Chr 6: 32.44 – 32.45 Mb	n/a
PubMed search

1A6A, 1AQD, 1BX2, 1D5M, 1D5X, 1D5Z, 1D6E, 1DLH, 1FV1, 1FYT, 1H15, 1HXY, 1J8H, 1JWM, 1JWS, 1JWU, 1KG0, 1KLG, 1KLU, 1LO5, 1PYW, 1R5I, 1SEB, 1SJE, 1SJH, 1T5W, 1T5X, 1YMM, 1ZGL, 2FSE, 2G9H, 2IAM, 2IAN, 2ICW, 2IPK, 2OJE, 2Q6W, 2WBJ, 2XN9, 3C5J, 3L6F, 3O6F, 3PDO, 3PGC, 3PGD, 3QXA, 3QXD, 3S4S, 3S5L, 3T0E, 4AEN, 4AH2, 4E41, 4FQX, 4GBX, 4H1L, 4C56, 4H25, 4H26, 4I5B, 4IS6, 4MCY, 4MCZ, 4MD0, 4MD4, 4MD5, 4MDI, 4MDJ, 4OV5, 4Y19, 4Y1A, 4X5X, 4X5W

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