HLA-DQB1

HLA-DQB1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1JK8, 1S9V, 1UVQ, 2NNA, 4GG6
Identifiers
Aliases	HLA-DQB1, CELIAC1, HLA-DQB, IDDM1, HLA-DQB1, major histocompatibility complex, class II, DQ beta 1, HLA-DRB1
External IDs	MGI: 103070 HomoloGene: 1603 GeneCards: HLA-DQB1
Gene ontology Molecular function • peptide antigen binding • MHC class II receptor activity Cellular component • integral component of membrane • endocytic vesicle membrane • clathrin-coated endocytic vesicle membrane • endosome • Golgi apparatus • trans-Golgi network membrane • endoplasmic reticulum membrane • membrane • Golgi membrane • plasma membrane • transport vesicle membrane • MHC class II protein complex • lysosomal membrane • endoplasmic reticulum • ER to Golgi transport vesicle membrane • lysosome • integral component of lumenal side of endoplasmic reticulum membrane • endosome membrane Biological process • antigen processing and presentation • antigen processing and presentation of exogenous peptide antigen via MHC class II • interferon-gamma-mediated signaling pathway • immunoglobulin production involved in immunoglobulin mediated immune response • immune system process • T cell costimulation • antigen processing and presentation of peptide or polysaccharide antigen via MHC class II • humoral immune response mediated by circulating immunoglobulin • immune response • T cell receptor signaling pathway Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3119	14961
Ensembl	n/a	ENSMUSG00000073421
UniProt	P01920	P14483 P01921 P06342 P06343 P06345 P06346
RefSeq (mRNA)	NM_002123 NM_001243961 NM_001243962	NM_207105
RefSeq (protein)	NP_001230890 NP_001230891 NP_002114	NP_996988.2 NP_996988
Location (UCSC)	Chr 6: 32.66 – 32.67 Mb	Chr 17: 34.26 – 34.27 Mb
PubMed search

1JK8, 1S9V, 1UVQ, 2NNA, 4GG6

3119

14961

n/a

ENSMUSG00000073421

P01920

P06346

NM_002123
NM_001243961
NM_001243962

NM_207105

NP_001230890
NP_001230891
NP_002114

NP_996988.2
NP_996988

Major histocompatibility complex, class II, DQ beta 1, also known as HLA-DQB1, is a human gene and also denotes the genetic locus that contains this gene. The protein encoded by this gene is one of two proteins that are required to form the DQ heterodimer, a cell surface receptor essential to the function of the immune system.

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Wikipedia