HEXIM1

HEXIM1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2GD7, 3S9G
Identifiers
Aliases	HEXIM1, CLP1, EDG1, HIS1, MAQ1, hexamethylene bis-acetamide inducible 1, hexamethylene bisacetamide inducible 1
External IDs	MGI: 2385923 HomoloGene: 31382 GeneCards: HEXIM1
Gene location (Human) Chr. Chromosome 17 (human) Band 17q21.31 Start 45,148,502 bp End 45,152,101 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 E1 Start 103,116,231 bp End 103,119,725 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • protein binding • snRNA binding • 7SK snRNA binding • cyclin-dependent protein serine/threonine kinase inhibitor activity Cellular component • nucleoplasm • cytoplasm • nucleus Biological process • positive regulation of signal transduction by p53 class mediator • heart development • regulation of transcription, DNA-templated • transcription, DNA-templated • negative regulation of cyclin-dependent protein serine/threonine kinase activity • negative regulation of transcription, DNA-templated • negative regulation of transcription from RNA polymerase II promoter • activation of innate immune response • immune system process • innate immune response Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10614	192231
Ensembl	ENSG00000186834	ENSMUSG00000048878
UniProt	O94992	Q8R409
RefSeq (mRNA)	NM_006460	NM_138753
RefSeq (protein)	NP_006451	NP_620092
Location (UCSC)	Chr 17: 45.15 – 45.15 Mb	Chr 17: 103.12 – 103.12 Mb
PubMed search

2GD7, 3S9G

10614

192231

ENSG00000186834

ENSMUSG00000048878

O94992

Q8R409

NM_006460

NM_138753

NP_006451

NP_620092

Protein HEXIM1 is a protein that in humans is encoded by the HEXIM1 gene.

HEXIM1 has been shown to interact with Cyclin T1.

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