HDAC7A

HDAC7

Protein HDAC7A PDB 2nvr.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3C0Y, 3C0Z, 3C10, 3ZNR, 3ZNS

Identifiers

HDAC7, HD7A, HDAC7A, HD7, histone deacetylase 7

External IDs

MGI: 1891835 HomoloGene: 9124 GeneCards: HDAC7

Genetically Related Diseases

Targeted by Drug

Belinostat, givinostat, panobinostat, quisinostat, romidepsin, trichostatin A

Gene ontology
Molecular function	• metal ion binding • transcription corepressor activity • protein kinase binding • 14-3-3 protein binding • hydrolase activity • protein kinase C binding • activating transcription factor binding • repressing transcription factor binding • chromatin binding • histone deacetylase activity • NAD-dependent histone deacetylase activity (H3-K14 specific) • protein binding • SUMO transferase activity
Cellular component	• nucleoplasm • cytoplasm • nucleus • histone deacetylase complex • cytosol
Biological process	• transcription, DNA-templated • negative regulation of NIK/NF-kappaB signaling • positive regulation of cell migration involved in sprouting angiogenesis • cell-cell junction assembly • vasculogenesis • negative regulation of transcription from RNA polymerase II promoter • histone H3 deacetylation • negative regulation of osteoblast differentiation • negative regulation of interleukin-2 production • regulation of transcription, DNA-templated • histone deacetylation • negative regulation of transcription, DNA-templated • covalent chromatin modification • chromatin organization • protein sumoylation
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE HDAC7A 217937 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


51564


56233


ENSG00000061273


ENSMUSG00000022475


Q8WUI4


Q8C2B3

RefSeq (mRNA)


NM_001098416 NM_001308090 NM_015401 NM_016596

NM_001204275 NM_001204276 NM_001204277 NM_001204278 NM_001204279
NM_001204280 NM_001204281 NM_019572

RefSeq (protein)


NP_001091886 NP_001295019 NP_056216

NP_001191204.1 NP_001191205.1 NP_001191206.1 NP_001191207.1 NP_062518.2
NP_001191204 NP_001191205 NP_001191206 NP_001191207 NP_001191208 NP_001191209 NP_001191210 NP_062518

Location (UCSC)

Chr 12: 47.78 – 47.83 Mb

Chr 15: 97.79 – 97.84 Mb

PubMed search

3C0Y, 3C0Z, 3C10, 3ZNR, 3ZNS

ENSG00000061273

ENSMUSG00000022475

NM_001098416
NM_001308090
NM_015401
NM_016596

NM_001204280
NM_001204281
NM_019572

NP_001091886
NP_001295019
NP_056216

NP_001191204
NP_001191205
NP_001191206
NP_001191207
NP_001191208
NP_001191209
NP_001191210
NP_062518

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Wikipedia

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