HABP2

HABP2
Identifiers
Aliases	HABP2, FSAP, HABP, HGFAL, PHBP, NMTC5, hyaluronan binding protein 2
External IDs	MGI: 1196378 HomoloGene: 3050 GeneCards: HABP2
Gene ontology Molecular function • peptidase activity • glycosaminoglycan binding • serine-type peptidase activity • hydrolase activity • calcium ion binding • serine-type endopeptidase activity Cellular component • extracellular region • extracellular space Biological process • cell adhesion • proteolysis Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3026	226243
Ensembl	ENSG00000148702	ENSMUSG00000025075
UniProt	Q14520	Q8K0D2
RefSeq (mRNA)	NM_004132 NM_001177660	NM_146101 NM_001329935 NM_001329936
RefSeq (protein)	NP_001171131 NP_004123	NP_666213.1 NP_001316864 NP_001316865 NP_666213
Location (UCSC)	Chr 10: 113.55 – 113.59 Mb	Chr 19: 56.29 – 56.32 Mb
PubMed search

3026

226243

ENSG00000148702

ENSMUSG00000025075

Q14520

Q8K0D2

NM_004132
NM_001177660

NM_146101
NM_001329935
NM_001329936

NP_001171131
NP_004123

NP_666213.1
NP_001316864
NP_001316865
NP_666213

Hyaluronan-binding protein 2 is a protein that in humans is encoded by the HABP2 gene.

The protein encoded by this gene is an extracellular serine protease which binds hyaluronic acid. It is involved in cell adhesion. The protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. Two transcript variants utilizing alternative polyA sites exist for this gene.

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