Glycoprotein IX

GP9
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3REZ
Identifiers
Aliases	GP9, CD42a, GPIX, Glycoprotein IX, glycoprotein IX platelet
External IDs	MGI: 1860137 HomoloGene: 144 GeneCards: GP9
Gene ontology Molecular function • protein binding Cellular component • integral component of membrane • plasma membrane • integral component of plasma membrane • membrane Biological process • platelet activation • blood coagulation, intrinsic pathway • hemostasis • cell adhesion • blood coagulation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2815	54368
Ensembl	ENSG00000169704	ENSMUSG00000030054
UniProt	P14770	O88186
RefSeq (mRNA)	NM_000174	NM_018762
RefSeq (protein)	NP_000165	NP_061232
Location (UCSC)	Chr 3: 129.06 – 129.06 Mb	Chr 6: 87.78 – 87.78 Mb
PubMed search

3REZ

2815

54368

ENSG00000169704

ENSMUSG00000030054

P14770

O88186

NM_000174

NM_018762

NP_000165

NP_061232

Glycoprotein IX (platelet) (GP9) also known as CD42a (Cluster of Differentiation 42a), is a human gene.

Platelet glycoprotein IX (GP9) is a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib (GP Ib), a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor (VWF; MIM 193400) (known as the Glycoprotein Ib-IX-V Receptor Complex). The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with GP9 and platelet glycoprotein V (GP5; MIM 173511).[supplied by OMIM]

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Wikipedia