Glycinamide ribonucleotide formyltransferase

GART
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1MEJ, 1MEN, 1MEO, 1NJS, 1RBM, 1RBQ, 1RBY, 1RBZ, 1RC0, 1RC1, 1ZLX, 1ZLY, 2QK4, 2V9Y, 4EW1, 4EW2, 4EW3, 4ZZ2, 4ZZ3, 4ZZ1, 4ZYV, 4ZZ0, 4ZYY, 4ZYX, 4ZYZ, 4ZYT, 4ZYU, 4ZYW
Identifiers
Aliases	GART, AIRS, GARS, GARTF, PAIS, PGFT, PRGS, phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
External IDs	OMIM: 138440 MGI: 95654 HomoloGene: 637 GeneCards: GART
Gene ontology Molecular function • transferase activity • nucleotide binding • phosphoribosylglycinamide formyltransferase activity • metal ion binding • ligase activity • catalytic activity • hydroxymethyl-, formyl- and related transferase activity • ATP binding • phosphoribosylformylglycinamidine cyclo-ligase activity • phosphoribosylamine-glycine ligase activity Cellular component • cytoplasm • cytosol • extracellular exosome Biological process • purine nucleotide biosynthetic process • glycine metabolic process • 'de novo' IMP biosynthetic process • brainstem development • biosynthetic process • response to organic substance • cerebellum development • ribonucleoside monophosphate biosynthetic process • tetrahydrofolate biosynthetic process • response to inorganic substance • purine ribonucleoside monophosphate biosynthetic process • cerebral cortex development • metabolic process • purine nucleobase biosynthetic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	2618	14450
Ensembl	n/a	ENSMUSG00000022962
UniProt	P22102	Q64737
RefSeq (mRNA)	NM_000819 NM_001136005 NM_001136006 NM_175085	NM_010256
RefSeq (protein)	NP_000810 NP_001129477 NP_001129478 NP_780294	NP_034386.2 NP_034386
Location (UCSC)	Chr 21: 33.5 – 33.54 Mb	Chr 16: 91.62 – 91.65 Mb
PubMed search

1MEJ, 1MEN, 1MEO, 1NJS, 1RBM, 1RBQ, 1RBY, 1RBZ, 1RC0, 1RC1, 1ZLX, 1ZLY, 2QK4, 2V9Y, 4EW1, 4EW2, 4EW3, 4ZZ2, 4ZZ3, 4ZZ1, 4ZYV, 4ZZ0, 4ZYY, 4ZYX, 4ZYZ, 4ZYT, 4ZYU, 4ZYW

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