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Glucose-6-phosphate

Glucose 6-phosphate
Glucose-6-Phosphate.svg
Beta-D-glucose-6-phosphate-3D-balls.png
Names
IUPAC name
D-Glucopyranose 6-phosphate
Identifiers
56-73-5 YesY
3D model (Jmol) Interactive image
ChEBI CHEBI:4170 YesY
ChemSpider 17216117 YesY
ECHA InfoCard 100.000.261
4647
MeSH Glucose-6-phosphate
PubChem 439284
Properties
C6H13O9P
Molar mass 260.136
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YesYN ?)
Infobox references

Glucose 6-phosphate (sometimes called the Robison ester) is a glucose sugar phosphorylated on carbon 6. This is a compound that is very common in cells as the vast majority of glucose entering a cell will become phosphorylated in this way.

Because of its prominent position in cellular chemistry, glucose 6-phosphate has many possible fates within the cell. It lies at the start of two major metabolic pathways: glycolysis and the pentose phosphate pathway. In addition to these two metabolic pathways, glucose 6-phosphate may also be converted to glycogen or starch for storage. This storage is in the liver and muscles in the form of glycogen for most multicellular animals, and in intracellular starch or glycogen granules for most other organisms.

Within a cell, glucose 6-phosphate is produced by phosphorylation of glucose on the sixth carbon. This is catalyzed by the enzyme hexokinase in most cells, and, in higher animals, glucokinase in certain cells, most notably liver cells. One molecule of ATP is consumed in this reaction.

Compound C00031 at KEGG Pathway Database. Enzyme 2.7.1.1 at KEGG Pathway Database. Compound C00668 at KEGG Pathway Database. Reaction R01786 at KEGG Pathway Database.


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