GluR5

GRM5

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3LMK, 4OO9, 5CGC, 5CGD

Identifiers

GRM5, GPRC1E, MGLUR5, PPP1R86, mGlu5, glutamate metabotropic receptor 5

External IDs

Gene ontology
Molecular function	• glutamate receptor activity • G-protein coupled receptor activity • signal transducer activity • G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential • neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
Cellular component	• cytoplasm • integral component of membrane • neuron projection • plasma membrane • integral component of plasma membrane • extracellular exosome • postsynaptic density of dendrite • membrane • presynaptic membrane
Biological process	• phospholipase C-activating G-protein coupled glutamate receptor signaling pathway • G-protein coupled glutamate receptor signaling pathway • G-protein coupled receptor signaling pathway • regulation of long-term neuronal synaptic plasticity • learning • cognition • locomotory behavior • signal transduction • chemical synaptic transmission • regulation of synaptic transmission, glutamatergic • adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway • regulation of postsynaptic membrane potential • regulation of postsynaptic cytosolic calcium ion concentration
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


2915


108071


ENSG00000168959


ENSMUSG00000049583


P41594


Q3UVX5

RefSeq (mRNA)


NM_000842 NM_001143831


NM_001033224 NM_001081414 NM_001143834

RefSeq (protein)


NP_000833 NP_001137303


NP_001074883 NP_001137306

Location (UCSC)

PubMed search

Metabotropic glutamate receptor 5 is a G protein-coupled receptor that in humans is encoded by the GRM5 gene.