The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) is an internationally agreed-upon system, created by the United Nations beginning in 1992 and as of 2015 is not yet fully implemented in many countries. It was designed to replace the various classification and labelling standards used in different countries by using consistent criteria on a global level. It supersedes the relevant system of the European Union, which has implemented the United Nations' GHS into EU law as the CLP Regulation and United States Occupational Safety and Health Administration standards.
Before the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) was created and implemented, there were many different regulations on hazard classification in use in different countries, resulting in multiple standards, classifications and labels for the same hazard. Given the extent of international trade in chemicals and the potential impact on neighboring countries when controls are not implemented, countries determined that a worldwide approach was necessary.
The GHS development began at the 1992 Rio Conference on Environment and Development by the United Nations also called Earth Summit (1992) when the International Labour Organization (ILO), the Organisation for Economic Co-operation and Development (OECD), various governments and other stakeholders agreed that "A globally harmonized hazard classification and compatible labelling system, including material safety data sheets and easily understandable symbols, should be available if feasible, by the year 2000".
The universal standard for all countries was to replace all the diverse classification systems; however, it has not been compulsory under UN law. The GHS provides the infrastructure for participating countries to implement a hazard classification and Hazard Communication Standard, which many less economically developed countries would not have had the money to create themselves. In the longer term, the GHS is expected to improve knowledge of the chronic health hazards of chemicals and encourage a move towards the elimination of hazardous chemicals, especially carcinogens, mutagens and reproductive toxicants, or their replacement with less hazardous ones.