"Ghosttown" is a song recorded by American singer Madonna for her thirteenth studio album, Rebel Heart (2015). It was released to radio stations on March 13, 2015, as the album's second single. The song was written by Madonna, Jason Evigan, Evan Bogart, and Sean Douglas, and produced by Madonna, Billboard and Evigan. Madonna had listened to Douglas's previous works and had requested studio time with him. Together with the other songwriters, they wrote "Ghosttown" in three days. A pop ballad, the song was inspired by the imagery of a destroyed city after armageddon, and how the survivors carry on with their lives, with love being the only thing they can hold onto. An uplifting track, "Ghosttown" features an organ and drums in its instrumentation, with minor vocoder effects on Madonna's vocals.

"Ghosttown" was released to iTunes Store as part of the album's pre-order in December 2014, in response to hackers leaking songs from Rebel Heart. The song received positive response from critics, who commended Madonna's vocal delivery, the lyrics, and Billboard's production; they also compared it to Madonna's earlier ballads. In the United States, the song became Madonna's 36th entry on the Adult Contemporary chart, as well as her 45th number-one song on the Hot Dance Club Songs chart, surpassing country singer George Strait as the artist with most number-one songs on an active Billboard chart. Internationally, "Ghosttown" reached the top twenty position in Hungary and Italy, and the digital charts of Finland and Sweden, and was certified platinum by the Federazione Industria Musicale Italiana (FIMI).

Madonna performed the song during her promotional schedules across Europe—Le Grand Journal in France, Che tempo che fa in Italy and The Jonathan Ross Show in the United Kingdom. She also performed it at the 2nd iHeartRadio Music Awards, where she was joined by Taylor Swift on guitar. An accompanying music video for "Ghosttown" was directed by Jonas Åkerlund, and starred actor Terrence Howard. The main theme behind the video was "an apocalyptic situation mimicking the end of the world", showing the singer and Howard as sole survivors in a destroyed city.

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