Colonel George Fane JP DL MP (c. 1616 – April 1663) was an English politician who sat in the House of Commons at various times between 1640 and 1663. He fought in the Royalist army in the English Civil War.
Colonel the Hon. George Fane was the fifth but fourth surviving son of Francis Fane, 1st Earl of Westmorland and his wife, Mary Mildmay (died 1640), daughter and heir of Sir Anthony Mildmay of Apethorpe, Northamptonshire. He was educated at Eton College from 1637 to 1632) and matriculated from Emmanuel College, Cambridge in 1632. He travelled abroad from 1635 to 1638, visiting Italy.
In 1640, Fane was elected Member of Parliament (MP) for Callington in Cornwall, a seat controlled by the Rolle family of Heanton Satchville, Petrockstowe. By 1642, he was a Captain of an Irish foot regiment and was Royalist lieutenant colonel by 1643. He was colonel of a foot regiment from 1644 to 1649 and fought as a colonel at Marston Moor.
Fane acquired the mortgage, in trust for his son, of a Thameside Berkshire estate at Basildon House in 1656 in the names of his sister, Lady Bath (who may have supplied the money) and his nephew, Charles Fane, Lord le Despenser (later the third Earl of Westmorland and 10th Baron le Despencer). Following the Restoration he was a Justice of the Peace and a Deputy Lieutenant for Berkshire until his death. He was a Commissioner for assessment for Warwickshire from August 1660 to 1661 and one for Berkshire from 1661 to 1663.