Genesis (2010) was a professional wrestling pay-per-view (PPV) event produced by the Total Nonstop Action Wrestling (TNA) promotion, which took place on January 17, 2010 at the TNA Impact! Zone in Orlando, Florida. It was the fifth event under the Genesis chronology and the first event of the 2010 TNA PPV schedule. The PPV poster was released in early December 2009, promoting Hulk Hogan's debut on TNA PPV. It is the first event since TNA moved to the Impact! Zone to feature a four-sided ring (as opposed to the typical six-sided ring used by TNA).

Genesis featured professional wrestling matches that involved different wrestlers from pre-existing scripted feuds and storylines. Wrestlers will be portrayed as villains, heroes or less distinguishable characters in the events that build tension and culminate into a wrestling match or series of matches.

The main rivalry showcased at Genesis was between Kurt Angle and defending champion A.J. Styles, both fighting for the TNA World Heavyweight Championship. Ric Flair made his debut in the company on the January 4, 2010 live episode of TNA Impact!, getting acquainted with A.J. Styles on a monumental night for the company, where in a high profile match, Styles retained his championship by defeating his competitive rival in Kurt Angle. By doing so, and for the past months, Styles solidified himself as champion successfully defending his title. Angle would later receive one last chance at the TNA World Heavyweight Championship, with Angle claiming that he only needed one more chance to be able to defeat Styles.

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