Galanin receptor 3

GALR3
Identifiers
Aliases	GALR3, Galanin receptor 3
External IDs	MGI: 1329003 HomoloGene: 20798 GeneCards: GALR3
Gene ontology Molecular function • peptide hormone binding • galanin receptor activity • G-protein coupled receptor activity • signal transducer activity Cellular component • integral component of membrane • plasma membrane • integral component of plasma membrane • membrane • non-motile cilium Biological process • learning or memory • phospholipase C-activating G-protein coupled receptor signaling pathway • G-protein coupled receptor signaling pathway • negative regulation of adenylate cyclase activity • neuropeptide signaling pathway • feeding behavior • positive regulation of transcription from RNA polymerase II promoter • signal transduction • adenylate cyclase-modulating G-protein coupled receptor signaling pathway • chemical synaptic transmission Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	8484	14429
Ensembl	ENSG00000128310	n/a
UniProt	O60755	O88853
RefSeq (mRNA)	NM_003614	NM_015738
RefSeq (protein)	NP_003605	NP_056553
Location (UCSC)	Chr 22: 37.82 – 37.83 Mb	n/a
PubMed search

8484

14429

ENSG00000128310

n/a

O60755

O88853

NM_003614

NM_015738

NP_003605

NP_056553

Galanin receptor 3 (GAL₃) is a G-protein coupled receptor encoded by the GALR3 gene.

The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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