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Galactose—1-phosphate uridylyltransferase

GALT
Galactose-1-phosphate uridylyltransferase 1GUP.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases GALT, entrez:2592, galactose-1-phosphate uridylyltransferase
External IDs OMIM: 606999 MGI: 95638 HomoloGene: 126 GeneCards: GALT
Gene location (Human)
Chromosome 9 (human)
Chr. Chromosome 9 (human)
Chromosome 9 (human)
Genomic location for GALT
Genomic location for GALT
Band 9p13.3 Start 34,638,133 bp
End 34,651,035 bp
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001258332
NM_000155

NM_016658
NM_001302511

RefSeq (protein)

NP_000146
NP_001245261

NP_001289440
NP_057867

Location (UCSC) Chr 9: 34.64 – 34.65 Mb Chr 9: 41.76 – 41.76 Mb
PubMed search
Galactose-1-phosphate uridyl transferase, N-terminal domain
Identifiers
Symbol GalP_UDP_transf
Pfam PF01087
Pfam clan CL0265
PROSITE PDOC00108
SCOP 1hxp
SUPERFAMILY 1hxp
Galactose-1-phosphate uridyl transferase, C-terminal domain
PDB 1gup EBI.jpg
structure of nucleotidyltransferase complexed with udp-galactose
Identifiers
Symbol GalP_UDP_tr_C
Pfam PF02744
Pfam clan CL0265
InterPro IPR005850
PROSITE PDOC00108
SCOP 1hxp
SUPERFAMILY 1hxp

5IN3

NM_001258332
NM_000155

NM_016658
NM_001302511

NP_000146
NP_001245261

NP_001289440
NP_057867

Galactose-1-phosphate uridylyltransferase (or GALT) is an enzyme (EC 2.7.7.12) responsible for converting ingested galactose to glucose.

Galactose-1-phosphate uridylyltransferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely:


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Wikipedia

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