GTF2H4

GTF2H4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5IY9, 5IVW, 5IY7, 5IY8, 5IY6
Identifiers
Aliases	GTF2H4, general transcription factor IIH, polypeptide 4, 52kDa, P52, TFB2, TFIIH, general transcription factor IIH subunit 4
External IDs	MGI: 1338799 HomoloGene: 7090 GeneCards: GTF2H4
Gene ontology Molecular function • protein kinase activity • DNA-dependent ATPase activity • transcription factor activity, sequence-specific DNA binding • ATP-dependent DNA helicase activity • protein binding • RNA polymerase II carboxy-terminal domain kinase activity • double-stranded DNA binding Cellular component • nucleoplasm • holo TFIIH complex • core TFIIH complex portion of holo TFIIH complex • core TFIIH complex • nucleus • transcription factor TFIID complex • nuclear speck Biological process • termination of RNA polymerase I transcription • regulation of transcription, DNA-templated • phosphorylation of RNA polymerase II C-terminal domain • transcription initiation from RNA polymerase I promoter • transcription elongation from RNA polymerase II promoter • 7-methylguanosine mRNA capping • transcription from RNA polymerase II promoter • transcription, DNA-templated • cellular response to DNA damage stimulus • global genome nucleotide-excision repair • transcription elongation from RNA polymerase I promoter • transcription-coupled nucleotide-excision repair • transcription initiation from RNA polymerase II promoter • nucleotide-excision repair, DNA incision • DNA repair • nucleotide-excision repair • nucleotide-excision repair, preincision complex stabilization • nucleotide-excision repair, DNA duplex unwinding • nucleotide-excision repair, preincision complex assembly • nucleotide-excision repair, DNA incision, 5'-to lesion • nucleotide-excision repair, DNA incision, 3'-to lesion • DNA duplex unwinding Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2968	14885
Ensembl	ENSG00000234370 ENSG00000236895 ENSG00000233149 ENSG00000221974 ENSG00000213780 ENSG00000226384	ENSMUSG00000001524
UniProt	Q92759	O70422
RefSeq (mRNA)	NM_001517	NM_010364
RefSeq (protein)	NP_001508	NP_034494
Location (UCSC)	Chr 6: 30.91 – 30.91 Mb	Chr 17: 35.67 – 35.67 Mb
PubMed search

5IY9, 5IVW, 5IY7, 5IY8, 5IY6

2968

14885

ENSG00000226384

ENSMUSG00000001524

Q92759

O70422

NM_001517

NM_010364

NP_001508

NP_034494

General transcription factor IIH subunit 4 is a protein that in humans is encoded by the GTF2H4 gene.

GTF2H4 has been shown to interact with:

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Wikipedia