GRID1

GRID1
Identifiers
Aliases	GRID1, GluD1, glutamate ionotropic receptor delta type subunit 1
External IDs	MGI: 95812 HomoloGene: 69017 GeneCards: GRID1
Gene ontology Molecular function • ion channel activity • extracellular-glutamate-gated ion channel activity • ionotropic glutamate receptor activity • receptor activity Cellular component • integral component of membrane • cell junction • postsynaptic membrane • plasma membrane • synapse • extracellular exosome • membrane Biological process • social behavior • ion transmembrane transport • ionotropic glutamate receptor signaling pathway • ion transport • transport • excitatory postsynaptic potential Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2894	14803
Ensembl	ENSG00000182771	ENSMUSG00000041078
UniProt	Q9ULK0	Q61627
RefSeq (mRNA)	NM_017551	NM_008166
RefSeq (protein)	NP_060021	NP_032192.2 NP_032192
Location (UCSC)	Chr 10: 85.6 – 86.37 Mb	Chr 14: 34.82 – 35.58 Mb
PubMed search

2894

14803

ENSG00000182771

ENSMUSG00000041078

Q9ULK0

Q61627

NM_017551

NM_008166

NP_060021

NP_032192.2
NP_032192

Glutamate receptor delta-1 subunit also known as GluD1 or GluRδ1 is a protein that in humans is encoded by the GRID1 gene.

This gene encodes a subunit of glutamate receptor ligand-gated ion channel. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.

Several genetic epidemiology studies have shown a strong association between several variants of the GRID1 gene and increased risk of developing schizophrenia.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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