GPA33
| GPA33 | |||||||||||||||||
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| Aliases | GPA33, A33, glycoprotein A33 | ||||||||||||||||
| External IDs | MGI: 1891703 HomoloGene: 4245 GeneCards: GPA33 | ||||||||||||||||
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| Species | Human | Mouse | |||||||||||||||
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| Location (UCSC) | Chr 1: 167.05 – 167.17 Mb | Chr 1: 166.13 – 166.17 Mb | |||||||||||||||
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Cell surface A33 antigen is a protein that in humans is encoded by the GPA33 gene.
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
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Wikipedia