GNRHR2

Identifiers

Aliases

GNRHR2, GnRH-II-R, gonadotropin releasing hormone receptor 2 (pseudogene)

External IDs

GeneCards: GNRHR2

Orthologs

Species

Human

Mouse

Entrez


114814


n/a

Ensembl


ENSG00000211451


n/a

UniProt


n/a


n/a

RefSeq (mRNA)


NM_057163 NM_206994


n/a

RefSeq (protein)


n/a


n/a

Location (UCSC)

Chr 1: 145.92 – 145.93 Mb

n/a

PubMed search

n/a

114814

n/a

ENSG00000211451

n/a

NM_057163
NM_206994

n/a

Putative gonadotropin-releasing hormone II receptor is a protein that in humans is encoded by the GNRHR2 gene.

The receptor for gonadotropin releasing hormone 2 (GnRH2) is encoded by the GnRH2 receptor (GnRHR2) gene. In non-hominoid primates and non-mammalian vertebrates, GnRHR2 encodes a seven-transmembrane G protein-coupled receptor. However, in human, the N-terminus of the predicted protein contains a frameshift and premature stop codon. In human, GnRHR2 transcription occurs but whether the gene produces a functional C-terminal multi-transmembrane protein is currently unresolved. Alternative splice variants have been reported. An untranscribed pseudogene of GnRHR2 is also on chromosome 14.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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